![]() Additionally, lactate could promote SCMV infection by suppressing plant defense responses. Moreover, LDH relocates in viral replicase complexes (VRCs) by interacting with SCMV-encoded 6K2 protein, a key protein responsible for inducing VRCs. The enzyme activity and transcriptional levels of lactate dehydrogenase (LDH) were up-regulated by SCMV infection, and LDH is essential for robust SCMV infection. ![]() Induction of lactate-involved anaerobic glycolysis is beneficial to SCMV infection. Here, we used untargeted metabolomics to reveal that lactate accumulates immediately before and after robust sugarcane mosaic virus (SCMV) infection. ![]() How viruses co-opt plant metabolism to support their successful infection remains an open question. Viruses often establish their own infection by altering host metabolism.
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